Table 2.

Reference genes for canine OS and their cellular function(s)

Gene symbol	Name	Function
RPS5	Ribosomal protein S5	Ribosomal protein that is a component of the 40S subunit, belongs to the S7P family of ribosomal proteins
RPS19	Ribosomal protein S19	Ribosomal protein that is a component of the 40S subunit, belongs to the S19E family of ribosomal proteins
HPRT	Hypoxanthine guanine phosphoribosyl transferase	Purine metabolism, salvage of purines from degraded RNA
HNRNPH	Heterogeneous nuclear ribonucleoprotein H	RNA-binding protein that forms a complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport
RPL8	Ribosomal protein L8	Ribosomal protein that is a component of the 60S subunit which catalyzes protein synthesis
GAPDH	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme in glycolysis and gluconeogenesis pathway
B2M	β-2-Microglobulin	Beta chain of MHC class I molecules
SRPR	Signal recognition particle receptor	Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system
GUSB	β-glucuronidase	Role in degradation of dermatan and keratin sulphates