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. 2017 Nov 25;17:792. doi: 10.1186/s12885-017-3789-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — a Typical p16 staining of both nucleus and cytoplasm of tumour cells (20X magnification). b Nuclear staining pattern of tumour cells by p53 antibody (20X magnification). c Nuclear staining pattern of pRb (20X magnification). d Low to strong Cyclin D1 staining of nuclei (20X magnification)