Table 3.

Sensitivity and specificity between HPV DNA detection by PCR (“positive result defined as disease for statistical testing”) and p16 by IHC

Point estimate		Confidence limits (95% CI)
Types	Value	Lower, upper
Sensitivity	72.22%	54.81% to 85.80%
Specificity	98.55%	94.86% to 99.82%
Positive Likelihood Ratio	49.83	12.40 to 200.21
Negative Likelihood Ratio	0.28	0.17 to 0.48
“Disease” prevalence	20.69% (a)	14.93% to 27.47%
Positive Predictive Value	92.86% (a)	76.50% to 99.12%
Negative Predictive Value	93.15% (a)	87.76% to 96.67%

^aDoes not reflect real prevalence of the “disease”