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. 2017 Nov 22;12:3353–3360. doi: 10.2147/COPD.S141798

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© 2017 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Effects of iloprost administration on gas exchange.

Notes: Top: for patients with nonsevere and severe COPD-PH, gas exchange before (open columns) and after (solid columns) iloprost treatment: (A) PaO₂, (B) D_A − _aO₂, and (C) Qs/Qt. Bottom: magnitude of changes induced by iloprost administration in (D) PaO₂ and (E) D_A − _aO₂. Values presented as mean ± standard error. *p<0.05 and **p<0.01 compared with corresponding values for patients with nonsevere COPD-PH.

Abbreviations: COPD-PH, pulmonary hypertension associated with COPD; D_A − _aO₂, alveolar–arterial oxygen partial pressure difference; PaO₂, partial pressure of oxygen in arterial blood; Qs/Qt, pulmonary shunt ratio.