Table 2.
Non-susceptibility rates of different genotypes of SA in pediatric population in China
| Isolates (n) | PEN | CXM | ERY | CLI | TET | GEN | CHL | RIF | CIP | SXT | LZD | VAN | MUP | TGC | FUS | MDRa | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MRSA | 60 | 96.7 | 38.4 | 100.0 | 83.3 | 40.0 | 5.0 | 63.3 | 3.3 | 20.0 | 0 | 0 | 0 | 0 | 0 | 1.7 | 76.7 |
| ST59-SCCmec IV-t437 | 37 | 97.3 | 45.9 | 100.0 | 91.9 | 54.1 | 2.7 | 70.3 | 2.7 | 18.9 | 0 | 0 | 0 | 0 | 0 | 0 | 83.8 |
| Others | 23 | 95.7 | 26.1 | 100.0 | 69.6 | 82.6 | 8.7 | 52.2 | 4.3 | 21.7 | 0 | 0 | 0 | 0 | 0 | 4.3 | 65.2 |
| MSSA | 44 | 95.5 | 0 | 100.0 | 31.8 | 18.2 | 25.0 | 61.4 | 0 | 13.6 | 0 | 0 | 0 | 0 | 0 | 0 | 77.3 |
| ST5-t002 | 4 | 75.0 | 0 | 100.0 | 75.0 | 25.0 | 75.0 | 50.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 75.0 |
| ST6-t701 | 4 | 100.0 | 0 | 100.0 | 0 | 0 | 0 | 75.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 75.0 |
| ST22-t309 | 8 | 100.0 | 0 | 100.0 | 12.5 | 12.5 | 0 | 37.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 62.5 |
| ST188-t189 | 4 | 100.0 | 0 | 100.0 | 25.0 | 25 | 25.0 | 75.0 | 0 | 25.0 | 0 | 0 | 0 | 0 | 0 | 0 | 75.0 |
| Others | 24 | 95.8 | 0 | 100.0 | 37.5 | 20.8 | 29.2 | 66.7 | 0 | 20.8 | 0 | 0 | 0 | 0 | 0 | 0 | 83.3 |
| Total | 104 | 96.2 | 22.1 | 100.0 | 61.5 | 30.8 | 13.4 | 62.5 | 1.9 | 17.3 | 0 | 0 | 0 | 0 | 0 | 0 | 85.6 |
| P value | 1.000 | <0.0001 | – | <0.0001 | 0.0193 | 0.0069 | 0.8408 | 0.5071 | 0.4431 | – | – | – | – | – | 1.000 | 1.000 |
PEN Penicillin, CXM Cefuroxime, ERY Erythromycin, CLI Clindamycin, TET Tetracycline, GEN Gentamicin, CHL Chloramphenicol, CIP Ciprofloxacin, RIF Rifampin, SXT Trimethoprim-sulfamethoxazole, LNZ Linezolid, VAN Vancomycin, MUP Mupirocin, TGC Tigecycline, FA Fusidic acid
a MDR multi-drug resistance. MDR-MRSA, resistant to ≥ 3 classes of non-β-lactam antimicrobials; MDR-MSSA, resistant to ≥ 3 classes of antibiotics including β-lactam antibiotics