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Similarities between human ASD and the MEK1-mediated mouse ASD model
| Human ASD | MEK1 ASD mouse model | |
|---|---|---|
| Gender distribution at birth | 51% male | 56% male |
| Gender dependent long term survival ate | 65% survivors were female (>5 years) | 89% survivors were female (21 days) |
| Major mortality stage | Early, first year after birth (75% of total death) | Early, before weaning (100% of death till 8wk old) |
| Growth impairment | Weight and length | Weight and length |
