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. 2017 Nov 25;11:114. doi: 10.1186/s12918-017-0500-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Summary of the major active pathways of central metabolism in the flux balance analysis simulation of the MitoCore model with default parameters and the objective function of maximum ATP production. Values of all fluxes are reported in Additional file 1.