Figure 2.

Trypanosoma cruzi-infected muMT mice exhibited high levels of TNF in plasma and body weight loss. Wild-type (WT) (n = 9, empty circles) and muMT (n = 13, blue circles) mice were infected with 10,000 trypomastigotes of T. cruzi Y strain. (A) Concentrations of IL-1b, IL-6, IL-12p70, INFγ, and TNF in plasma at different days post infection (Dpi). (B) Body weight of infected WT or muMT mice at different Dpi (100% was considered at 0 Dpi). Data are shown as mean ± SD (*p < 0.05, **p < 0.01, ***p < 0.001, two-way ANOVA, Bonferroni post-test). Experiment representative of 4.