Table 2.

Effects of Dichrocephala integrifolia on acetylcholinesterase activity, malondialdehyde and reduced glutathione levels of scopolamine treated mice.

Treatments (for 10 days)	Dose (mg/kg)	AchE (μmol/min/mg protein)	MDA (μmol/mg protein)	GSH (μmol/mg protein)
DW + Sal	– + –	11.98 ± 1.13∗∗∗	0.12 ± 0.04∗∗∗	20.00 ± 1.77∗∗∗
DW + Sco	– + 1	29.41 ± 6.42c	0.61 ± 0.12c	12.33 ± 1.05c
DI + Sco	35 + 1	22.89 ± 3.88a	0.53 ± 0.09c	13.00 ± 1.05c
DI + Sco	87.5 + 1	13.25 ± 3.88∗∗∗	0.29 ± 0.22b∗∗	24.66 ± 2.43∗∗∗
DI + Sco	175 + 1	19.19 ± 4.00∗	0.35 ± 0.09∗	20.33 ± 1.40∗a
DI + Sco	350 + 1	19.88 ± 6.64∗	0.28 ± 0.08∗∗	19.83 ± 1.81a∗
Tac + Sco	10 + 1	12.52 ± 7.46∗∗∗	0.21 ± 0.06∗∗∗	27.5 ± 0.67∗∗∗

Results are expressed as mean ± SEM for six mice, ^∗p < 0.05, ^∗∗p < 0.001, ^∗∗∗p < 0.0001 compare to scopolamine alone treated group (DW + Sco). ^ap < 0.05, ^bp < 0.001, ^cp < 0.0001 compare to control mice (DW + Sal). DW, distilled water; DI, D. integrifolia; Sal, saline; Sco, scopolamine; Tac, tacrine.