Figure 6.

Prediction of pp65-specific CD8⁺ T cell responses in a certain individual based on the database of pp65-specific CD8⁺ T cell responses in each human leukocyte antigen (HLA) class I allotype. Based on the mean frequency of pp65-specific CD8⁺ T cells in each HLA class I allotypes obtained from 50 healthy donors, the sum of CD8⁺ T cell responses in each HLA class I allotype present in an individual was calculated as the predicted CD8⁺ T cell response, which was compared with the observed CD8⁺ T cell response. The predicted CD8⁺ T cell response was the most significant when the response was below 600. P and R values were calculated by Pearson’s correlation analysis.