Figure 1.

Patient‐derived somatic cells from a patient with neuropsychiatric disease are reprogrammed into hiPSCs via Yamanaka factors. Patient‐specific hiPSCs are then induced to differentiate into NPCs, neurons, and organoids. These disease‐relevant cells provide a platform for research approaches such as transcriptomic, genomic, and biochemical analyses, as well as analyses of neuronal circuit integration, neuronal ion channel properties, neuronal morphology, and other neuronal phenotypes. Abbreviations: hiPSCs, human induced pluripotent stem cells; NPCs, neural progenitor cells.