Table 1.

Approaches used in the investigation of human induced pluripotent stem cells (hiPSCs) and hiPSC‐derived tissue relating to neuropsychiatric disorders

Assay	hiPSC	NPC	Neuron	Organoid
Immunohistochemistry / protein assay	[28], [29], [30], [31], [32], [33], [34],[35]	[36], [29], [30], [31], [32], [35]	[36], [29], [30], [31], [32], [33], [35]	[34]
Transcriptomic and epigenomic profiling	[28], [30], [31]	[36], [31], [25], [34]	[36], [28], [29], [30], [31], [32]	[34]
Growth / proliferation	[34], [35]	[29], [31], [35]
Neurite / synapse morphology			[36], [31], [32], [33], [35]	[34]
Electrophysiology			[36], [31], [32], [33], [34], [35]	[34]
Biochemical assay / response		[31], [33]	[36], [32], [37], [35]

Numbers in table refer to references.

Color Legend: Green: Bipolar Disorder.

Blue: Schizophrenia.

Red: Autism.

Orange: Rett syndrome (monogenic, syndromic autism).

Light blue: Fragile X syndrome (monogenic, syndromic ASD).

Purple: Timothy syndrome (monogenic, syndromic ASD).

Abbreviation: NPCs, neural progenitor cells.