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In vivo fluorescence localization of the breast tissue specific conjugate in MCF-7 tumor xenograft model. (A) Nude mice were injected intravenously with the breast tissue specific conjugate 3B (10 mg/kg), and were examined using a MAESTRO in vivo fluorescence imaging system. (B) Fluorescence was detected in the MCF-7 tumor xenograft immediately after the administration of 3B. (C) Main route of elimination of the nontoxic drug delivery conjugate may be through urinary excretion.
