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. 2017 Nov 22;4:206. doi: 10.3389/fmed.2017.00206

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Copyright © 2017 Kaplan and Maas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Development of spontaneous plasma kallikrein-like activity in factor XII (FXII)-deficient plasma after depletion of C1-INH. (A) Chromogenic substrate conversion assay. (B) Western blot for HK cleavage.