Table 1.

Applications and examples of biomarkers.

Usefulness	Example	Analytical method	Reference
Narrows diagnostic possibilities	C4 levels for HAE	ELISA	(2)
Correlates with disease activity	Anti-dsDNA for systemic lupus erythematosus	ELISA	(3)
Has prognostic significance	BRCA1/2 for breast cancer	PCR	(4)