Table 2.

Properties of an “ideal” biomarker in angioedema.

Patient management Offer improved patient diagnosis Ability to stratify patients by severity Assist in therapeutic management (improve patient quality of life)

Biomarker choice Easily accessible sample type (e.g., blood) Long half-life in blood Pathobiologic link to disease mechanism

Assay Sensitive and specific test Robust assay method (comparable results across multiple labs) Potential for rapid test