Table 2.
Summary of analysis of variance (repeated measures ANOVA) for normalized quantitative anisotropy (NQA).
| Within-subjects effects (ANCOVA) | |||||
|---|---|---|---|---|---|
| Interaction | |||||
| Source | Brain areas | Type III sum of squares | Mean square | F(1, 24) | Significancea (NQA) |
| Time (pre and post) × group (ALT/BLT) (sphericity assumed) | Body of CC | 0.004 | 0.004 | 4.932 | 0.036* |
| Left anterior corona radiata | 0.005 | 0.005 | 9.460 | 0.005* | |
| Thalamus | 0.003 | 0.003 | 5.688 | 0.025* | |
| Pairwise comparisons (pre versus post) | |||||
| Effect of treatment | Brain areas | Groups | F(1, 24) | Significancea (NQA) | |
| Pre versus post | Body of CC | ALT | 0.604 | 0.445 | |
| BLT | 5.984 | 0.022** | |||
| Left anterior corona radiata | ALT | 0.903 | 0.351 | ||
| BLT | 12.347 | 0.002** | |||
| Thalamus | ALT | 0.352 | 0.558 | ||
| BLT | 8.226 | 0.008** | |||
NQA, normalized quantitative anisotropy; BLT, blue-light therapy; ALT, amber-light therapy; CC, corpus callosum; ANCOVA, analysis of covariance.
aAdjustment for multiple comparisons using Bonferroni’s method.
*Interaction is significant at p < 0.05.
**Mean difference between post- and pre-treatment is significant at p < 0.05.