Table 3.
Summary of correlations between residualized changes in neuropsychological function measures (DM) and GFA, and between residualized changes in MSLT scores and normalized quantitative anisotropy (NQA) measures.
| # | ROIs | Partial correlations (r, p) between residualized changes in |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| GFA and |
NQA and |
||||||||||
| DM | MSLT 1 | MSLT 2 | MSLT 3 | Mean MSLT | DM | MSLT 1 | MSLT 2 | MSLT 3 | Mean MSLT | ||
| BLT group | |||||||||||
| 1 | Splenium of CC | 0.35, 0.27 | −0.33, 0.29 | −0.17, 0.60 | −0.48, 0.12 | −0.37, 0.23 | – | ||||
| 2 | Body of CC | – | −0.76, 0.00** | −0.18, 0.58 | −0.43, 0.16 | −0.17, 0.60 | −0.37, 0.24 | ||||
| 3 | ACR (L) | – | −0.37, 0.23 | −0.72, 0.01** | −0.45, 0.14 | −0.45, 0.15 | −0.58, 0.05 | ||||
| 4 | Thalamus | – | −0.64, 0.02** | −0.45, 0.14 | −0.48, 0.11 | −0.39, 0.21 | −0.54, 0.07 | ||||
| ALT group | |||||||||||
| 1 | Splenium of CC | −0.02, 0.96 | −0.56, 0.06 | −0.61, 0.04* | −0.38, 0.22 | −0.61, 0.04* | – | ||||
| 2 | Body of CC | – | 0.19, 0.55 | −0.52, 0.08 | −0.52, 0.08 | −0.51, 0.09 | 0.60, 0.04* | ||||
| 3 | ACR (L) | – | 0.43, 0.16 | 0.18, 0.57 | 0.04, 0.91 | −0.04, 0.92 | 0.07, 0.83 | ||||
| 4 | Thalamus | – | −0.07, 0.83 | 0.13, 0.70 | −0.19, 0.56 | 0.42, 0.17 | 0.17, 0.60 | ||||
ROIs, regions of interest; GFA, generalized fractional anisotropy; NQA, normalized quantitative anisotropy; DM, delayed memory; MSLT, multiple sleep latency test; BLT, blue-light therapy; CC, corpus callosum; ACR (L), anterior corona radiata (left); ALT, amber-light therapy; FDR, false discovery rate.
*p < 0.05 (uncorrected for multiple comparisons).
**p < 0.05 (FDR corrected for multiple comparisons).