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. 2017 Sep 26;292(47):19338–19355. doi: 10.1074/jbc.M117.796441

Table 1.

Measurements for TBP-binding dynamics at select promoters with a full model fit

TBP-full model kxla τxlb ka·CTFc kdd Ssate Kf t½g θbh
1/mol s s 1/s 1/s mol s
ACT1 0.14 (+31.2, −0.51) 2.76 (+45.05, −0.73) 3.21 (+1.3, −0.92) E-04 6.98 (+3.3, −2.2) E-03 1.35 (+0.35, −0.28) 2.61 (+1.0, −0.74) E-04 99.3 (+99.32, −56.51) 0.044 (+0.44, −0.016)
LOS1 NAi NA 6.31 (+1.1, −0.93) E-04 8.58 (+2.3, −1.8) E-03 0.44 (+0.031, −0.029) 1.63 (+0.32, −0.27) E-04 80.8 (+21.45, −16.94) 0.069 (+0.012, 0.01)
URA1 0.30 (+1129.02, −4.74) 1.29 (+19.22, −0.081) 7.59 (+1.0, −0.91) E-04 1.0 (+0.29, −0.23) E-02 0.71 (+0.036, −0.035) 1.62 (+0.36, −0.29) E-04 67.7 (+21.02, −16.2) 0.069 (+0.015, −0.01)

a Formaldehyde cross-linking rate is shown.

b Cross-linking time is shown.

c On-rate of transcription factor X nuclear concentration of factor is shown.

d Off-rate of transcription factor is shown.

e ChIP signal at saturation is shown.

f Dissociation constant, kd/ka is shown.

g Residence time of TF binding is shown.

h Occupancy is shown.

i NA means not applicable.