Table 2.
Measurements for TBP-binding dynamics at select promoters with a linear model fit
| TBP-linear | kxl·Ssata | τxlb | ka·CTFc | kdd | Ssate | Kf | t½g | θbh |
|---|---|---|---|---|---|---|---|---|
| 1/mol s | s2 | 1/s | 1/s | mol | s | |||
| NTS2 | 1.1 (+0.084, −0.078) E-03 | NAi | NA | NA | NA | 4.51 (+2.21, −1.44) E-06 | NA | 0.73 (+0.077, −0.07) |
| SNR6 | 1.7 (+0.12, −0.11) E-03 | NA | NA | NA | NA | 4.46 (+2.0, −1.37) E-06 | NA | 0.73 (+0.074, −0.067) |
| HSC82 | 3.4 (+0.54, −0.47) E-04 | NA | NA | NA | NA | 8.96 (+5,73, −3.51) E-06 | NA | 0.57 (+0.13, −0.1) |
a Formaldehyde cross-linking rate × ChIP signal at saturation is shown.
b Cross-linking time is shown.
c On-rate of transcription factor X nuclear concentration of factor is shown.
d Off-rate of transcription factor is shown.
e ChIP signal at saturation is shown.
f Dissociation constant, kd/ka is shown.
g Residence time of TF binding is shown.
h Occupancy is shown.
i NA means not applicable.