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Effect of glucose on the cellular ratios of nicotinamide nucleotides, cytosolic redox couples, and adenine nucleotides in the absence and presence of metformin. Values from Figs. 5 and 6 were used to calculate ratios of some redox (A–E) and adenine nucleotides couples (F and G) of interest in INS1 (832/13) cells treated with 5 mm metformin (white symbols) or vehicle (black symbols). Pyr, pyruvate; Lac, lactate.
