Figure 1.
Expression of Orai and STIM1 in distal PAs from rats exposed to normoxia or hypoxia (10% O2) for 21 days. Orai1 (a), Orai2 (b), Orai3 (c) and STIM1 (d) mRNA relative to 18 s was measured by qRT-PCR. Orai1, 2, 3 and STIM1 proteins were determined by western blotting (e and f). Representative blots (e) and mean intensity (f) for Orai1, 2, 3 and STIM1 blots relative to α-actin. Bar values are mean±S.E.M. (n=5 in each group). *P<0.05 versus respective normoxic control. Brackets indicate ±S.E.