Figure 2.

HCAL Is Overexpressed in HCC and Is Clinically Correlated with the Poor Prognosis of Patients with HCC

(A) HCAL expression in 84 pairs of HCC and corresponding peritumor tissues was analyzed by performing qPCR. ***p < 0.001 (paired Student’s t test). (B) HCAL expression in the immortalized normal liver cells (LO2 cells) and seven HCC cell lines was analyzed by performing qPCR. LO2 cells were used as controls. *p < 0.05 (Student’s t test). (C and D) Kaplan-Meier survival curves and log rank tests were used to evaluate the association of HCAL expression with (C) recurrence-free and (D) overall survival of patients with HCC. The patients were divided into high- and low-HCAL groups based on median HCAL expression in HCC tissues.