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. Author manuscript; available in PMC: 2017 Nov 27.
Published in final edited form as: Cell Rep. 2017 Nov 21;21(8):2236–2250. doi: 10.1016/j.celrep.2017.10.102

Figure 3. dKO Mice are Capable of Repetitive Muscle Regeneration.

Figure 3

(A) Protocol for assessing injury-induced regeneration.

(B) H&E-stained sections from control and dKO TA muscles subjected to one or three injuries; IF of Pax7 and laminin in TA sections. Arrows indicate SCs. Insets show higher magnification. Scale bar, 20μm.

(C) Box and whisker plots for cross-sectional areas of fibers from the regenerated region of TA after triple injury.

(D) Quantification of Pax7+ cells in TA sections from control and dKO mice prior to injury and after single and triple injury. *, p<0.005, means±SD.

(E) Ratio of Pax7+ cells in dKO vs. control mice prior to injury and after single and triple injury.