Table 2. Clinical characteristics of patients in the COPD and healthy control groups.
| Subject characteristics | Control (n = 101) |
COPD (n = 101) |
p-value |
|---|---|---|---|
| Age, mean ± SEM, years | 52.9 ± 1.1 | 55.6 ± 0.9 | 0.070a |
| Gender, M/F | 69/32 | 85/16 | 0.008b |
| Height, mean ± SEM, cm | 161.1 ± 0.9 | 160.2 ± 0.9 | 0.460a |
| Weight, mean ± SEM, kg | 62.8 ± 1.3 | 50.6 ± 1.0 | 0.001a |
| BMI, mean ± SEM, kg/m2 | 24.1 ± 0.4 | 19.8 ± 0.4 | 0.001a |
| Smoking, never/smoker | 68/33 | 28/73 | 0.001b |
| Pack years, mean ± SEM | 18.7 ± 1.3 | 32.8 ± 1.8 | 0.001a |
| Post FVC, mean ± SEM, % | 88.7 ± 0.9 | 59.7 ± 1.4 | 0.001a |
| Post FEV1 predicted, mean ± SEM, % | 89.8 ± 0.7 | 37.6 ± 1.0 | 0.001a |
| Post FEV1/FVC, mean ± SEM, % | 101.6 ± 0.7 | 61.2 ± 0.7 | 0.001a |
Data were expressed in mean ± standard error of the mean (SEM). p < 0.050 was considered significant. aUnpaired t-test, bchi-square test; FVC: forced vital capacity; BMI: body mass index; FEV1: forced expiratory volume in the first second; COPD: chronic obstructive pulmonary disease.