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. Author manuscript; available in PMC: 2017 Nov 27.
Published in final edited form as: J Matern Fetal Neonatal Med. 2015 Mar 23;29(3):360–367. doi: 10.3109/14767058.2015.1006621

Table 4.

Pregnancy outcomes according to the results of point of care IL-6 (using cut-off: 745 pg/ml)

Negative point of care IL-6 (Group 1) (n=22) Positive point of care IL-6 (Group 2) (n=34) P value
Amniotic fluid glucose (mg/dl) 25.5 (11.5–32.75) 14 (10–22) 0.01
Amniotic fluid WBC (cell/m3) 4.5 (0–38) 27 (6.8–262.5) 0.01
Gestational age at amniocentesis (weeks) 30.65 (28–31.78) 27 (22.7–30.48) 0.005
Microbial invasion of the amniotic cavity (MIAC) 18.2% (4/14) 29.4% (10/34) 0.34
Gestational age at delivery (weeks) 31.8 (30.6–33.18) 28.9 (23.48–32.78) 0.008
Delivery < 28 week (n=19) 50% (2/4) 89.5% (17/19) 0.06
Delivery < 34 week (n=54) 95.5% (21/22) 97.1% (33/34) 0.75
Birthweight (grams) 1752.5 (1398.8–2108.8) 1220 (524–1777.5) 0.03
ELISA amniotic fluid IL-6 (pg/ml) 1091.7 (701.1–1965.6) 12 328.1 (6138.7–132 198.2) <0.001
Acute histologic chorioamnionitis (n=15) 36.4% (4/11) 73.3% (11/15) 0.06
Acute funisitis (n=12) 27.3% (3/11) 60% (9/15) 0.098

AF: amniotic fluid; GA: gestational age; WBC: white blood cell; ELISA: enzyme linked immunosorbent assay; IL: interleukin.