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. 2017 Nov 22;11:2073–2089. doi: 10.2147/OPTH.S140110

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© 2017 Guha Mazumder et al. This work is published and licensed by Dove Medical Press Limited

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ROC curve generated from the ¹H-NMR spectral data to identify serum metabolomic biomarkers for neuroretinal degeneration.

Notes: (A) Fructose-6-phosphate, (B) glycerophosphocholine, (C) ribitol, (D) UDP-Glc-NAc of DM and DR, showing the fold change of metabolites, with sensitivity and specificity of classification model in discriminating between DM and DR.

Abbreviations: AUC, area under the curve; DM, diabetes mellitus; DR, diabetic retinopathy; NMR, nuclear magnetic resonance; ROC, receiver operating characteristic; UDP-Glc-NAc, uridine 5′-diphosphate-N-acetyl glucosamine.