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. 2017 Nov 23;9:691–700. doi: 10.2147/CMAR.S149801

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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ROC curve analysis of different CTC subsets in a large cohort of breast cancer patients.

Notes: (A–C) ROC curves for (A) E+/M+, (B) M+ and (C) E+/M+ plus M+ CTCs in the large cohort of breast cancer patients are shown. The AUC values show the ability of these CTCs to predict distant metastasis in breast cancer patients.

Abbreviations: AUC, area under the curve; CTCs, circulating tumor cells; ROC, receiver operating characteristic; E+ CTCs, exclusively epithelial CTCs; E+/M+ CTCs, biphenotypic epithelial/mesenchymal CTCs; M+ CTCs, exclusively mesenchymal CTCs.