Figure 2.

Timing of MBZ application with respect to IR.

Notes: (A) MBZ was applied for a 6-hour time frame beginning 6 hours pre IR followed by washout of the drug. During this time period, both mitotic and interphase cells were present. (B) MBZ was applied for a 6-hour time frame beginning 3 hours post IR followed by washout of the drug. During this time period, the mitotic cell population was absent (composed entirely of interphase cells). (C) MBZ was applied beginning 6 hour pre IR and left in the medium for the duration of the experiment.

Abbreviations: IR, ionizing radiation; MBZ, mebendazole.