Table 2.

Univariate and multivariate analyses of prognostic factors for overall survival using Cox proportional hazards regression model (N=93)

Variables	Overall survival	HR (95%) CI
	Univariate analysis
	P-value
Gender
Male vs female	0.35	1.316 (0.740–2.341)
Age
≤60 vs >60	0.955	0.986 (0.609–1.598)
Pathological types
SCC vs ADC	0.824	0.943 (0.562–1.583)
Primary tumor (T) stage
T1–2 vs T3–4	0.020*	0.549 (0.331–0.911)
Lymph node (N) metastasis
N0–1 vs N2–3	0.172	0.699 (0.418–1.168)
Clinical tumor/node/metastasis stage
II vs III	0.354	0.772 (0.446–1.335)
RKIP expression
Low vs high	0.003*	1.810 (0.617–5.313)
Variables	Overall survival	HR (95%) CI
	Multivariate analysis
	P-value
Primary tumor (T) stage
T1–2 vs T3–4	0.386	0.767 (0.421–1.398)
RKIP expression
Low vs high	0.042#	1.830 (1.023–3.276)

Note:

^*P<0.05 by univariate Cox proportional hazards regression model,

^#P<0.05 by multivariate Cox proportional hazards regression model.

Abbreviations: ADC, adenocarcinoma; HR, hazard ratio; RKIP, Raf kinase inhibitor protein; SCC, squamous cell carcinoma.