Table V.
Correlation of individual cytokines by PBMCs from prepartum vs postpartum mothers, mothers vs fathers, mothers vs 3-mo infants, and fathers vs 3-mo infants
|
Samples from |
Pearson Correlation Coefficients (n)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Samples from mothers prepartum
| ||||||||
| IFN-γ | IL-4 | IL-13 | IL-5 | IL-10 | IFN-γ:IL-4 | IFN-γ:IL-13 | IFN-γ:IL-10 | |
| Mothers postpartum | 0.197a (379) | 0.365a (381) | 0.272a (369) | 0.325a (357) | 0.345a (384) | 0.450a (360) | 0.425a (361) | 0.446a (361) |
| Fathers | 0.027 (313) | 0.093 (330) | 0.095 (296) | 0.141 (294) | 0.210a (315) | 0.016 (306) | 0.055 (284) | −0.059 (290) |
| Infants at 3 mo | 0.081 (281) | 0.091 (290) | 0.080 (264) | NCb | −0.120 (292) | 0.098 (277) | 0.155 (261) | 0.001 (277) |
|
| ||||||||
| Samples from | Samples from mothers postpartum
|
|||||||
| IFN-γ | IL-4 | IL-13 | IL-5 | IL-10 | IFN-γ:IL-4 | IFN-γ:IL-13 | IFN-γ:IL-10 | |
|
| ||||||||
| Fathers | 0.150c (343) | 0.179a (349) | 0.183a (335) | 0.035 (328) | 0.256a (323) | 0.043 (334) | 0.062d (323) | −0.030 (312) |
| Infants at 3 mo | 0.167a (302) | 0.137 (298) | 0.207a (294) | NC | 0.101 (299) | 0.138 (292) | 0.239a (290) | 0.033 (0.571) |
|
| ||||||||
| Samples from | Samples from fathers
|
|||||||
| IFN-γ | IL-4 | IL-13 | IL-5 | IL-10 | IFN-γ:IL-4 | IFN-γ:IL-13 | IFN-γ:IL-10 | |
|
| ||||||||
| Infants at 3 mo | 0.163c (244) | 0.043 (252) | 0.161 (228) | NC | 0.106 (235) | 0.152 (242) | 0.140 (219) | 0.120 (227) |
a
Significant at the 0.001 level (two tailed).
b
NC, Not computed because of the large proportion of undetectable IL-5 values.
c
Significant at the 0.01 level (two tailed).
d
Not significant by Pearson but Spearman ρ = 0.165, p = 0.003.