Table 1.
Demographic and Clinical Characteristics of the Study Groups.
| Variable | HIV− 1 (n=42) | HAND− 2 (n=50) | HAND+ 3 (n=43) | Group Effects* |
|---|---|---|---|---|
| Sociodemographics | ||||
| Age (years) | 44.3 (12.8) | 46.5 (9.6) | 45.2 (10.5) | ----- |
| Education (years) | 13.9 (2.2) | 14.1 (2.7) | 13.1 (2.1) | ----- |
| Sex (% women) | 31.0 | 8.0 | 11.6 | 1 > 2, 3 |
| Ethnicity (%) | ----- | |||
| Caucasian | 52.4 | 62.0 | 48.8 | |
| Hispanic | 21.4 | 16.0 | 23.3 | |
| Black | 21.4 | 16.0 | 23.4 | |
| Other | 4.8 | 6.0 | 4.7 | |
| Psychiatric | ||||
| Major Depression (%) | 26.2 | 55.1 | 69.8 | 1 < 2, 3 |
| Generalized Anxiety (%) | 11.9 | 6.4 | 18.6 | ----- |
| POMS Total (of 200) | 39.2 (30.1) | 45.5 (30.0) | 59.9 (42.2) | 1 < 3 |
| * Alcohol Use Disorder (%) | 40.5 | 43.8 | 51.2 | ----- |
| * Substance Use Disorder (%) | 33.3 | 51.0 | 46.5 | ----- |
| Medical | ||||
| Hepatitis C (%) | 13.9 | 10.4 | 11.9 | ----- |
| AIDS (%) | ----- | 52.1 | 57.1 | ----- |
| Duration of HIV (years) | ----- | 12.0 (9.7) | 14.1 (8.6) | ----- |
| Nadir CD4 (cells/μL) | ----- | 256.0 (208.3) | 217.1 (227.6) | ----- |
| Current CD4 (cells/μL) | ----- | 699.7 (331.8) | 606.8 (332.4) | ----- |
| Plasma HIV RNA (% detectable on ART) | ----- | 2.3 | 16.2 | 2 < 3 |
| ART (% prescribed) | ----- | 92.0 | 93.0 | ----- |
| Everyday Functioning | ||||
| Global Functioning (% dependent) | 16.7 | 40.0 | 62.8 | 3 > 2 > 1 |
| Employment (% unemployed) | 47.6 | 44.0 | 65.1 | ----- |
| Karnofsky (% disabled) | 2.3 | 13.3 | 25.6 | 3>1,2 |
| ADL (% dependent) | 16.3 | 30.0 | 39.5 | 3>1 |
| PAOFI (% symptomatic) | 11.9 | 44.0 | 55.8 | 2,3>1 |
| UPSA Total | 78.5 (11.3) | 83.2 (11.6) | 74.3 (13.7) | 2 > 3 |
Note: POMS = Profile of Mood States. AIDS = Acquired Immune Deficiency Syndrome. ART = antiretroviral therapy.
*
Denotes any lifetime disorder