Table 3.
Genes relating to G protein signaling, Metabolism and Signal Transduction that were differentially expressed by γδ T cells from all five M. bovis-infected calves in response to stimulation with PPD-b
| Pathway | Gene | Name | Fold Change |
|---|---|---|---|
| G Protein Signaling | CXCL10 | Interferon gamma induced protein 10 | 80726.06 ± 31605.93 |
| LOC504773 | Regakine-1 | 6.87E-02 ± 3.74E-02 | |
| PTAFR | Platelet-activating factor receptor | 0.0145 ± 0.009 | |
| EDNRB | Endothelin B receptor | 0.0014 ± 0.001 | |
| ADM | ADM Adrenomedullin-11-26 Proadrenomedullin N-20 terminal peptide | 7285.56 ± 4096.94 | |
| Metabolism | APOE | Apolipoprotein E | 3.01E-02 ± 1.95E-02 |
| STXBP1 | Syntaxin-binding protein 1 | 5310.15 ± 2220.27 | |
| HMOX1 | Heme oxygenase 1 | 2.25E-02 ± 1.91E-02 | |
| CD36 | Platelet glycoprotein 4 | 5.18E-05 ± 1.14E-05 | |
| HBA | Hemoglobin subunit alpha | 19829.58 ± 7702.57 | |
| INHBA | Inhibin beta A chain | 7737.023 ± 8867.88 | |
| TNF | Tumor necrosis factor | 13.09 ± 3.16 | |
| Signal Transduction | |||
| CISH | Cytokine-inducible SH2-containing protein | 10123.22± 8427.81 | |
| ISG15 | Ubiquitin-like protein ISG15 | 34.81 ± 12.26 | |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.045 ± 0.016 |
Values are ± SEM