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. 2017 Aug 31;8(5):573–582. doi: 10.1080/19491034.2017.1348449

Figure 4.

Figure 4.

Characterization of novel LMNA isoforms through lentiviral overexpression. (A) Schematic representation of the components of the GFP-LMNA isoform construct used in lentiviral experiments. (B) Representative immunofluorescence images of DAPI stain, GFP signal, and lamin B1 stain in cell lines overexpressing GFP-LMNA, GFP-LMNAΔ150, GFP-LMNAΔ447, and GFP-LMNAΔ297. Scale bar size: 10 μm. (C) Quantification of lamin B1 (LMNB1) signal from 4 independent experiments (n>900 cells total). Significant differences in expression from cells overexpressing GFP-LMNA are indicated *p<0.05.