LMNA isoform mRNA expression levels in young and aged cell lines. Levels of LMNA, LMNAΔ150, and LMNAΔ447 were measured by ddPCR in primary fibroblast cultures from biologically young (n = 9) and old donors (n = 10). (A) Average levels of LMNA expression for young and old groups. Difference in expression is non-significant (n.s.); (p>0.05, 2 tailed students T-test), SD are indicated. (B) Average levels of LMNAΔ150 expression for young and old groups. Difference in expression is non-significant (p>0.05), SD are indicated. (C) Average levels of LMNAΔ447 expression for young and old groups. Difference in expression is non-significant (p>0.1, 2 tailed students T-test), SD are indicated. Complete data for individual cell lines is given in Suppl. Fig. S5.