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. 2017 Jan 4;26(3):637–649. doi: 10.1093/hmg/ddw401

Table 6.

Results of aPTT meta-analysis for models 1 and 2

rs_locus A1 A2 Freq1 Beta SE P-value Direction P_het
Model 1
rs710446 C T 0.412164 −0.296423 0.009575 2.29 × 10−210 6.10 × 10−04
rs4253417 C T 0.419123 −0.118784 0.009575 2.65 × 10−35 0.194202
rs4253421 G A 0.885623 −0.083696 0.009575 2.44 × 10−18 −+– 0.130280
rs76438938 T C 0.028115 −0.056257 0.009575 4.33 × 10−09 0.877173
rs780094 C T 0.592274 0.014700 0.009575 0.124693  +++ 0.770329
Model 2
rs710446 C T 0.411999 −0.204035 0.009579 1.28 × 10−100 4.54 × 10−05
rs4253417 C T 0.418964 −0.042991 0.009579 7.28 × 10−06 −+– 0.614175
rs4253421 G A 0.885574 −0.031183 0.009579 0.001138 − ++ 0.255919
rs76438938 T C 0.028138 −0.007322 0.009579 0.444662 − +++ 0.280294
rs780094 C T 0.592396 −0.004186 0.009579 0.662094 −+– 0.700256

Results from the GWAMA fixed-effect meta-analysis based on normalized beta and standard errors. Because of the inflated heterogeneity for rs710446 in both model 1 and model 2 analyses, we performed a random-effect version of these analyses that confirmed the discovered association for this SNP (Supplementary Material, Table S9).