Table 3.

Hepatotoxicity among TB/HIV-coinfected participants on TB treatment

	Unadjusted hazard ratio (HR)			Adjusted hazard ratio (HR)
Characteristic	HR	95% CI	P value	HR	95% CI	P value
Age	1.00	0.97–1.02	1.00	0.99	0.97–1.03	0.994
BMI	1.04	0.97–1.12	0.238	1.07	0.97–1.14	0.185
Male sex	0.97	0.59–1.61	0.926	1.01	0.65–1.95	0.673
CD4 cell count
≤250 cells/mm3	0.84	0.45–1.57	0.579	0.89	0.44–1.59	0.603
>250 cells/mm3	0.66	0.38–1.21	0.178	0.51	0.35–1.18	0.045
Rifampicin Cmax	1.85	0.63–5.42	0.264	1.80	0.50–6.48	0.368
Isoniazid Cmax	1.06	0.37–3.06	0.911	0.65	0.18–2.29	0.499