Table 3.

Vaccine compliance: doses received by 24 months.

		Compliance Measurea
					Vaccinated Late		Severe Undervaccinationb		Total Number of Days Undervaccinatedc
Compliance Measure		No Doses on Time, %	All Doses on Time, %	P Value	%	P Value	%	P Value	Mean	SE	Median	P Value
4 DTaP	Total	7.94	56.47		43.53		13.92		204.32	5.67	150.24
	At least 1 combo vaccine	5.59	58.34	< 0.001	41.66	< 0.001	11.54	< 0.001	178.34	5.21	150.04	< 0.001
	No combo vaccines	22.03	45.17		54.83		28.19		322.96	17.54	186.69
3 IPV	Total	5.56	76.92		23.08		7.60		204.32	5.67	80.32
	At least 1 combo vaccine	2.69	80.06	< 0.001	19.94	< 0.001	4.68	< 0.001	144.06	7.93	62.68	< 0.001
	No combo vaccines	22.83	58.05		41.95		25.17		364.92	18.18	399.16
1 MMR	Total	21.14	78.86		21.14		9.80		147.59	3.48	168.39
	At least 1 combo vaccine	18.56	81.44	< 0.001	18.56	< 0.001	7.37	< 0.001	135.27	3.91	116.96	< 0.001
	No combo vaccines	36.65	63.35		36.65		24.36		185.09	7.44	236.52
Hib	Total	10.19	41.86		58.14		27.17		221.37	4.72	157.71
	At least 1 combo vaccine	7.62	43.38	< 0.001	56.62	< 0.001	24.83	< 0.001	202.73	4.73	142.96	< 0.001
	No combo vaccines	25.65	32.75		67.25		41.25		315.73	15.24	241.70
4 Hib	Total	8.13	43.25		56.75		24.90		203.20	4.66	130.97
	At least 1 combo vaccine	7.32	44.04	< 0.001	55.96	< 0.001	23.80	0.113	197.76	4.95	126.35	< 0.001
	No combo vaccines	13.93	37.66		62.34		32.70		237.93	14.08	198.45
3 Hib	Total	14.33	31.51		68.49		42.27		271.83	11.01	245.38
	At least 1 combo vaccine	12.78	30.03	< 0.001	69.97	< 0.001	45.42	0.569	278.99	11.85	246.16	< 0.001
	No combo vaccines	21.12	37.98		62.02		28.48		236.51	28.01	162.77
3 HepB	Total	7.48	61.34		38.66		11.94		207.34	6.79	106.65
	At least 1 combo vaccine	5.96	64.45	< 0.001	35.55	< 0.001	8.95	< 0.001	171.88	6.48	99.26	< 0.001
	No combo vaccines	16.62	42.62		57.38		29.92		339.40	19.64	197.36
1 varicella	Total	21.54	78.46		21.54		10.27		150.09	3.44	169.02
	At least 1 combo vaccine	18.78	81.22	< 0.001	18.78	< 0.001	7.70	< 0.001	137.55	3.78	117.25	< 0.001
	No combo vaccines	38.14	61.86		38.14		25.72		187.23	7.15	241.23
Rotavirus	Total	21.47	59.09		40.91		31.90		470.56	7.02	576.80
	At least 1 combo vaccine	18.24	61.73	< 0.001	38.27	< 0.001	29.05	< 0.001	454.36	7.93	576.34	< 0.001
	No combo vaccines	40.85	43.20		56.80		49.06		536.17	13.99	637.21
3 rotavirus	Total	5.71	69.94		30.06		19.52		364.66	10.32	504.73
	At least 1 combo vaccine	5.44	70.22	< 0.001	29.78	0.445	19.36	0.197	364.21	10.95	504.60	< 0.001
	No combo vaccines	7.75	67.78		32.21		20.75		367.85	30.15	468.21
2 rotavirus	Total	7.05	76.66		23.34		10.81		287.91	25.94	74.11
	At least 1 combo vaccine	6.50	78.16	< 0.001	21.84	< 0.001	9.71	0.507	277.29	27.53	72.98	< 0.001
	No combo vaccines	13.46	59.37		40.63		23.48		354.10	79.02	200.66
4 PCV	Total	11.35	50.47		49.53		50.48		250.73	5.99	189.79
	At least 1 combo vaccine	8.63	52.47	< 0.001	47.53	< 0.001	47.53	< 0.001	229.78	6.34	152.61	< 0.001
	No combo vaccines	27.68	38.44		61.56		64.19		348.03	16.22	292.05
4:3:1:3:3:1d	Total	3.06	25.86		74.14		38.25		254.44	4.52	205.70
	At least 1 combo vaccine	0.93	27.56	< 0.001	72.44	< 0.001	35.37	< 0.001	233.09	4.45	174.63	< 0.001
	No combo vaccines	15.86	15.66		84.34		55.53		364.72	14.93	322.06
4:3:1:3:3:1:4e	Total	3.06	22.89		77.11		42.65		276.06	4.64	241.13
	At least 1 combo vaccine	0.93	24.46	< 0.001	75.54	< 0.001	39.85	< 0.001	255.61	4.72	220.88	< 0.001
	No combo vaccines	15.86	13.43		86.57		59.48		383.36	14.72	349.37

DTaP = diphtheria, tetanus toxoid, and acellular pertussis vaccine; HepB = hepatitis B vaccine; Hib = Haemophilus influenzae type b vaccine; IPV = inactivated poliovirus vaccine; MMR = measles, mumps, and rubella vaccine; PCV = pneumococcal conjugate vaccine; SE = standard error of the mean.

^aCompliance is an assessment of receipt of doses at age-appropriate intervals.

^bSevere undervaccination is defined as having 7 months or more of cumulative undervaccination.

^cTotal number of days undervaccinated is the total count of cumulative days undervaccinated.

^dThe 4:3:1:3:3:1 series includes 4 DTaP, 3 IPV, 1 MMR, 3 or 4 Hib, 3 hepatitis B, and 1 varicella recommended by age 24 months.

^eThe 4:3:1:3:3:1:4 series includes 4 DTaP, 3 IPV, 1 MMR, 3 or 4 Hib, 3 hepatitis B, 1 varicella, and 4 PCV recommended by age 24 months.