Table 3.
Compliance Measurea |
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Vaccinated Late |
Severe Undervaccinationb |
Total Number of Days Undervaccinatedc |
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Compliance Measure | No Doses on Time, % | All Doses on Time, % | P Value | % | P Value | % | P Value | Mean | SE | Median | P Value | |
4 DTaP | Total | 7.94 | 56.47 | 43.53 | 13.92 | 204.32 | 5.67 | 150.24 | ||||
At least 1 combo vaccine | 5.59 | 58.34 | < 0.001 | 41.66 | < 0.001 | 11.54 | < 0.001 | 178.34 | 5.21 | 150.04 | < 0.001 | |
No combo vaccines | 22.03 | 45.17 | 54.83 | 28.19 | 322.96 | 17.54 | 186.69 | |||||
3 IPV | Total | 5.56 | 76.92 | 23.08 | 7.60 | 204.32 | 5.67 | 80.32 | ||||
At least 1 combo vaccine | 2.69 | 80.06 | < 0.001 | 19.94 | < 0.001 | 4.68 | < 0.001 | 144.06 | 7.93 | 62.68 | < 0.001 | |
No combo vaccines | 22.83 | 58.05 | 41.95 | 25.17 | 364.92 | 18.18 | 399.16 | |||||
1 MMR | Total | 21.14 | 78.86 | 21.14 | 9.80 | 147.59 | 3.48 | 168.39 | ||||
At least 1 combo vaccine | 18.56 | 81.44 | < 0.001 | 18.56 | < 0.001 | 7.37 | < 0.001 | 135.27 | 3.91 | 116.96 | < 0.001 | |
No combo vaccines | 36.65 | 63.35 | 36.65 | 24.36 | 185.09 | 7.44 | 236.52 | |||||
Hib | Total | 10.19 | 41.86 | 58.14 | 27.17 | 221.37 | 4.72 | 157.71 | ||||
At least 1 combo vaccine | 7.62 | 43.38 | < 0.001 | 56.62 | < 0.001 | 24.83 | < 0.001 | 202.73 | 4.73 | 142.96 | < 0.001 | |
No combo vaccines | 25.65 | 32.75 | 67.25 | 41.25 | 315.73 | 15.24 | 241.70 | |||||
4 Hib | Total | 8.13 | 43.25 | 56.75 | 24.90 | 203.20 | 4.66 | 130.97 | ||||
At least 1 combo vaccine | 7.32 | 44.04 | < 0.001 | 55.96 | < 0.001 | 23.80 | 0.113 | 197.76 | 4.95 | 126.35 | < 0.001 | |
No combo vaccines | 13.93 | 37.66 | 62.34 | 32.70 | 237.93 | 14.08 | 198.45 | |||||
3 Hib | Total | 14.33 | 31.51 | 68.49 | 42.27 | 271.83 | 11.01 | 245.38 | ||||
At least 1 combo vaccine | 12.78 | 30.03 | < 0.001 | 69.97 | < 0.001 | 45.42 | 0.569 | 278.99 | 11.85 | 246.16 | < 0.001 | |
No combo vaccines | 21.12 | 37.98 | 62.02 | 28.48 | 236.51 | 28.01 | 162.77 | |||||
3 HepB | Total | 7.48 | 61.34 | 38.66 | 11.94 | 207.34 | 6.79 | 106.65 | ||||
At least 1 combo vaccine | 5.96 | 64.45 | < 0.001 | 35.55 | < 0.001 | 8.95 | < 0.001 | 171.88 | 6.48 | 99.26 | < 0.001 | |
No combo vaccines | 16.62 | 42.62 | 57.38 | 29.92 | 339.40 | 19.64 | 197.36 | |||||
1 varicella | Total | 21.54 | 78.46 | 21.54 | 10.27 | 150.09 | 3.44 | 169.02 | ||||
At least 1 combo vaccine | 18.78 | 81.22 | < 0.001 | 18.78 | < 0.001 | 7.70 | < 0.001 | 137.55 | 3.78 | 117.25 | < 0.001 | |
No combo vaccines | 38.14 | 61.86 | 38.14 | 25.72 | 187.23 | 7.15 | 241.23 | |||||
Rotavirus | Total | 21.47 | 59.09 | 40.91 | 31.90 | 470.56 | 7.02 | 576.80 | ||||
At least 1 combo vaccine | 18.24 | 61.73 | < 0.001 | 38.27 | < 0.001 | 29.05 | < 0.001 | 454.36 | 7.93 | 576.34 | < 0.001 | |
No combo vaccines | 40.85 | 43.20 | 56.80 | 49.06 | 536.17 | 13.99 | 637.21 | |||||
3 rotavirus | Total | 5.71 | 69.94 | 30.06 | 19.52 | 364.66 | 10.32 | 504.73 | ||||
At least 1 combo vaccine | 5.44 | 70.22 | < 0.001 | 29.78 | 0.445 | 19.36 | 0.197 | 364.21 | 10.95 | 504.60 | < 0.001 | |
No combo vaccines | 7.75 | 67.78 | 32.21 | 20.75 | 367.85 | 30.15 | 468.21 | |||||
2 rotavirus | Total | 7.05 | 76.66 | 23.34 | 10.81 | 287.91 | 25.94 | 74.11 | ||||
At least 1 combo vaccine | 6.50 | 78.16 | < 0.001 | 21.84 | < 0.001 | 9.71 | 0.507 | 277.29 | 27.53 | 72.98 | < 0.001 | |
No combo vaccines | 13.46 | 59.37 | 40.63 | 23.48 | 354.10 | 79.02 | 200.66 | |||||
4 PCV | Total | 11.35 | 50.47 | 49.53 | 50.48 | 250.73 | 5.99 | 189.79 | ||||
At least 1 combo vaccine | 8.63 | 52.47 | < 0.001 | 47.53 | < 0.001 | 47.53 | < 0.001 | 229.78 | 6.34 | 152.61 | < 0.001 | |
No combo vaccines | 27.68 | 38.44 | 61.56 | 64.19 | 348.03 | 16.22 | 292.05 | |||||
4:3:1:3:3:1d | Total | 3.06 | 25.86 | 74.14 | 38.25 | 254.44 | 4.52 | 205.70 | ||||
At least 1 combo vaccine | 0.93 | 27.56 | < 0.001 | 72.44 | < 0.001 | 35.37 | < 0.001 | 233.09 | 4.45 | 174.63 | < 0.001 | |
No combo vaccines | 15.86 | 15.66 | 84.34 | 55.53 | 364.72 | 14.93 | 322.06 | |||||
4:3:1:3:3:1:4e | Total | 3.06 | 22.89 | 77.11 | 42.65 | 276.06 | 4.64 | 241.13 | ||||
At least 1 combo vaccine | 0.93 | 24.46 | < 0.001 | 75.54 | < 0.001 | 39.85 | < 0.001 | 255.61 | 4.72 | 220.88 | < 0.001 | |
No combo vaccines | 15.86 | 13.43 | 86.57 | 59.48 | 383.36 | 14.72 | 349.37 |
DTaP = diphtheria, tetanus toxoid, and acellular pertussis vaccine; HepB = hepatitis B vaccine; Hib = Haemophilus influenzae type b vaccine; IPV = inactivated poliovirus vaccine; MMR = measles, mumps, and rubella vaccine; PCV = pneumococcal conjugate vaccine; SE = standard error of the mean.
Compliance is an assessment of receipt of doses at age-appropriate intervals.
Severe undervaccination is defined as having 7 months or more of cumulative undervaccination.
Total number of days undervaccinated is the total count of cumulative days undervaccinated.
The 4:3:1:3:3:1 series includes 4 DTaP, 3 IPV, 1 MMR, 3 or 4 Hib, 3 hepatitis B, and 1 varicella recommended by age 24 months.
The 4:3:1:3:3:1:4 series includes 4 DTaP, 3 IPV, 1 MMR, 3 or 4 Hib, 3 hepatitis B, 1 varicella, and 4 PCV recommended by age 24 months.