Prescribed conditions in larger vessels (at input/output nodes of 1D pipe elements mesh)
Inlet Pressure	3999.7 Pa (30 mmHg)
Outlet Pressure	1333.2 Pa (10 mmHg)
Inlet Concentration	Bolus - C(t) (Fig. 19 dashed line)
Outlet Concentration	0 molar
Characteristics of fluid/diffusion flow through blood vessels (large vessels and capillaries)
Viscosity	10−3 Pa s
Diffusion coefficient	1000 mm2/s
Characteristics of blood vessel walls:
Hydraulic permeability coefficient	10−12 mm / (Pa s)
Diffusion coefficient	0.1 mm2 /s
Thickness	10% of vessel diameter
Characteristics of tissue
Diffusion coefficient	0.1 mm2/s
Darcy coefficient	10−12 mm2 /(Pa s)
Smeared model:
Average capillary diameter	0.025 mm
Capillary wall thickness	0.0025 mm
Volume fraction	10%
Diffusion coefficient of capillary wall:	10−6 mm2 / s
Hydraulic permeability of capillary wall:	10−12 mm / (Pa s)
Time steps:	40 × 10 s