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. 2017 Nov 27;12(11):e0188678. doi: 10.1371/journal.pone.0188678

Table 1. Characteristic data of the subjects.

Stage one Stage two
ADHD Control Statistics P value ADHD Control Statistics P value
(256) (372) 2 or t) (328) (431) 2 or t)
Age(mean±SD)a 8.20±1.53 8.34±1.72 1.048 0.148 8.51±1.78 8.60±2.10 0.624 0.266
Gender(boys: girls) 0.324 0.570 3.157 0.076
Boys 201 299 263 322
girls 55 73 65 109
IQ score(mean±SD) a 96.57±12.35 97.52±11.25 1.000 0.159 89.33±11.21 90.49±11.60 1.385 0.083
Maternal stress pregnancy
No 149 256 7.460 0.006 251 349 4.700 0.030
Yes 107 116 77 72
Maternal smoking
No 241 356 0.785 0.376 314 422 3.013 0.083
Yes 15 16 14 9
Maternal alcohol
No 239 359 3.299 0.069 311 415 0.969 0.325
Yes 17 13 17 16
Parental marital status
Couple 229 350 4.525 0.033 314 416 3.013 0.083
Divorced 27 22 14 12
Preterm birth
≥37 weeks 214 330 3.425 0.064 298 380 2.870 0.090
<37 weeks 42 42 30 51
Low birth weight
<2.5kg 34 28 5.643 0.018 35 29 3.749 0.053
≥2.5 kg 222 344 293 402
Blood lead levelb
Low 117 202 6.783 0.009 152 228 3.205 0.073
High 149 169 176 203
Subtype
Inattentive(ADHD-I) 102(40%) 138(42%)
Hyperactive/impulsive(ADHD-HI) 64(25%) 79(24%)
Combined(ADHD-C) 90(35%) 111(34%)
PSQ score(mean±SD) a
Impulsive-hyperactive score 1.36±1.20 1.27±1.05 -0.995 0.160 1.52±0.84 1.45±0.82 -1.153 0.125
Hyperactive score 1.32±0.41 1.24±0.42 -2.368 0.009 1.58±0.92 1.36±0.96 -3.184 0.001
Total score 38.98±17.56 37.86±11.15 -0.977 0.164 40.21±18.02 38.97±16.59 -0.983 0.163

a mean ± SD, by independent t-test;

b Stage one: low <Median 54.50ug/l, High≥54.50 ug/l; Stage two: low <Median 55.05ug/l, High≥55.05ug/l; Bold values indicated P< 0.05.