Table 6. Interaction analysis between environmental factors and polymorphisms associated with ADHD risk in combined samples.
| Genotypes | factors | Case/control | OR(95%CI) | Pamul | Paadd |
|---|---|---|---|---|---|
| rs1541665 | Maternal stress pregnancy | 0.021 | 0.034 | ||
| TT | No | 189/312 | 1.000 | ||
| TT | Yes | 29/74 | 0.658(0.458,1.041) | ||
| CT+CC | No | 211/293 | 1.189(0.954,1.587) | ||
| CT+CC | Yes | 155/84 | 3.052(2.219,4.271) | ||
| rs1541665 | Blood lead level* | ||||
| TT | Low(<54.70ug/l) | 148/272 | 1.000 | 0.154 | 0.017 |
| TT | High(≥54.70 ug/l) | 70/114 | 1.236(0.798,1.639) | ||
| CT+CC | Low(<54.70ug/l) | 132/141 | 1.731(1.263,2.471) | ||
| CT+CC | High(≥54.70 ug/l) | 234/276 | 1.674(1.299,2.478) |
*Blood lead level was divided into low and high by median (54.70 ug/l).
a All the P values were adjusted for age and gender.
The significant results were in bold.