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. 2017 Nov 27;12(11):e0188534. doi: 10.1371/journal.pone.0188534

Table 2. [Dry eye study] Patient demographics and univariate comparisons of clinical parameters.

Control Glaucoma P-value A
No. subjects 1431 89
Age (years) 66.9 ± 9.7 67.9 ± 9.2 n.s.
No. males/females 534/897 45/44 0.013*
Dry eye-related symptoms
Dryness +/- 345/1086 19/70 n.s.
Eye fatigue +/- 456/975 25/64 n.s.
Photophobia +/- 247/1176 11/78 n.s.
Pain +/- 93/1333 5/84 n.s.
Blurring +/- 273/1151 18/71 n.s.
Dry eye-related signs
Schirmer test (≤ 5 mm/> 5mm) 46/134 2/8 n.s.
Tear break-up time (≤ 5s/> 5s) 700/726 49/39 n.s.
Corneal staining score 0.32 ± 0.61 0.36 ± 0.64 n.s.
Topical medications other than prostaglandin (% of cases)
None 62.5 53.8 0.866
Sodium hyarulonate 12.4 22.0 0.127
Mucin secretagogue 12.2 13.2
Steroid + Hyarulonate 3.1 0.0
OthersB 9.8 11.0 0.702

Unless indicated otherwise, data are given as the mean ± SD.

AP-values were obtained by Chi-squared test and the Mann–Whitney U test, as appropriate; asterisks indicate significant differences.

Bother medications included Kary® Uni and Sancoba®.