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. 2017 Nov 27;12(11):e0188097. doi: 10.1371/journal.pone.0188097

Table 2. Frequency and mean (±SD) baseline clinical and metabolic characteristics of the studied cohort according to the life status.

Variables Diabetic patients without foot complications Diabetic foot patients
Foot ulcer Lower extrimities Amputation (LEA)
Alive
750(89.3%)
Deceased
90(10.7%)
P value* Alive
439(81.9%)
Deceased
97(18.1%)
P value* Alive
206(67.8%)
Deceased
98(32.2%)
P value*
Mean Age (years) 60.31(±11.99) 68.87(±10.35) <0.001 60.20(±11.38) 66.22(±12.54) <0.001 61.53(±10.41) 66.85(±11.86) <0.001
Age 25–44 years 44(5.87%) 1(1.11%) 0.001 21(4.78%) 5(5.16%) 0.186 6(2.91%) 5(5.10%) 0.494
45–64 years 310(41.33%) 23(25.56%) 203(46.24%) 35(36.08%) 84(40.78%) 35(35.71%)
≥65 years 396(52.80%) 66(73.33%) 215(48.97%) 57(58.76%) 116(56.31%) 58(59.18%)
Gender Men 488(65.07%) 66(73.33%) 0.118 271(61.73%) 74(76.29%) 0.007 133(64.56%) 76(77.55%) 0.022
Women 262(34.93%) 24(26.67%) 168(38.27%) 23(23.71%) 73(35.44%) 22(22.45%)
Type of diabetes Type 1 46(6.13%) 2(2.22%) 0.154 28(6.38%) 7(7.22%) 0.762 8(3.88%) 3(3.06%) 0.976
Type2 704(93.87%) 88(97.78%) 411(93.62%) 90(92.78%) 198(96.12%) 95(96.94%)
Mean DM duration (years) 17.93(±7.16) 21.03(±6.99) <0.001 19.08(±7.84) 21.47(±7.26) 0.006 20.37(±8.27) 21.88(±7.84) 0.132
DM duration <10 years 51(6.80%) 3(3.33%) 0.259 30(6.83%) 2(2.06%) 0.095 10(4.85%) 4(4.08%) 0.764
≥10 years 699(93.20%) 87(96.67%) 409(93.17%) 95(97.94%) 196(95.15%) 94(95.92%)
Diabetes Treatment Oral agents 364(48.53%) 41(45.56%) 0.010 127(28.93%) 31(31.96%) 0.001 41(19.90)% 20(20.41%) 0.047
Insulin only 192(25.60%) 36(40.00%) 189(43.05%) 58(59.79%) 121(58.74%) 68(69.39%)
Both 194(25.87%) 13(14.44%) 123(28.02%) 8(8.25%) 44(21.36%) 10(10.20%)
Mean Weight (kg) 77.47(±15.31) 73.22(±13.68) 0.029 79.84(±16.40) 72.20(±12.62) <0.001 77.36(±17.10) 74.71(±17.02) 0.311
Mean Height (cm) 161.09(±9.46) 160.39(±9.58) 0.586 161.84(±9.76) 161.45(±10.61) 0.763 161.32(±7.90) 162.45(±7.47) 0.373
Mean BMI (kg/m2) 29.96(±6.04) 28.74(±5.60) 0.134 30.37(±6.69) 27.62(±5.04) <0.001 29.68(±5.66) 28.47(±5.65) 0.206
BMI <25 kg/m2 158(21.07%) 25(27.78%) 0.359 96(21.87%) 30(30.93%) 0.009 32(15.53%) 21(21.43%) 0.616
25–29.9 kg/m2 264(35.20%) 33(36.67%) 143(32.57%) 42(43.30%) 93(45.15%) 41(41.84%)
≥30 kg/m2 328(43.73%) 32(35.55%) 200(45.56%) 25(25.77%) 81(39.32%) 36(36.73%)
Smoking 49(6.53%) 9(10.00%) 0.202 34(7.74%) 17(17.53%) 0.016 15(7.28%) 9(9.18%) 0.732
Macrovascular complications 114(15.20) 30(33.33) <0.001 84(19.13) 35(36.08) <0.001 54(26.21) 56(57.14) <0.001
Microvascular complications 345(46.00) 54(60.00) 0.003 439(100.00) 96(98.97) 0.033 205(99.51) 98(100.00) 0.490
Hypertension 392(52.27%) 65(72.22%) <0.001 228(51.94%) 59(60.82%) 0.112 118(57.28%) 69(70.41%) 0.028
Hyperlipidemia 287(38.27%) 32(35.56%) 0.608 174(39.64%) 28(28.87%) 0.041 69(33.50%) 26(26.53%) 0.203
Mean FBS (mmol/L) 10.69(±4.56) 11.10(±3.77) 0.612 11.36(±5.03) 12.91(±5.51) 0.126 11.08(±4.92) 11.02(±5.97) 0.956
Mean RBS (mmol/L) 13.61(±5.58) 14.88(±5.78) 0.350 13.79(±5.69) 15.22(±5.14) 0.231 13.12(±5.46) 15.68(±6.46) 0.068
Mean HbA1c 9.20(±2.20) 9.13(±1.31) 0.923 9.63(±2.05) 9.67(±1.11) 0.940 9.37(±2.32) 11.54(±3.24) 0.024
HbA1c <8 mmol/L 239(31.87%) 22(24.44%) 0.151 94(21.41%) 9(9.28%) 0.460 77(37.38%) 20(20.41%) 0.306
≥8 mmol/L 511(68.13%) 68(75.56%) 345(78.59%) 88(90.72%) 129(62.62%) 78(79.59%)

*P value between deceased and alive.