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. 2017 Nov 27;12(11):e0188097. doi: 10.1371/journal.pone.0188097

Table 3. All-cause and standardized mortality ratios (SMRs) for diabetic patients without foot complications, diabetic foot ulcer (DFU), and lower extremity amputation (LEA).

Variables Observed number of deaths Person years Mortality /1000/ person years Expected Number of deaths SMR (95% CI) Mortality rate ratios (95% CI)
Diabetic patients without foot complications
All 90 3,780 23.81 35.36 2.53(2.03–3.03) -
gender Men 66 2,444 27.00 29.54 2.23(1.64–2.02) 1.08(0.67–1.75)
Women 24 1,336 17.96 8.62 2.78(1.90–3.66) 1
Duration of diabetes ≤15 years 9 584 15.41 5.1 1.76(0.69–2.83) 1
>15 years 81 3,196 25.34 30.45 2.66(2.10–3.22) 2.94(1.44–5.98) *
Age < 65 years 24 1,725 13.91 2.99 8.01(6.73–9.29) -
≥ 65 years 66 2,055 32.12 32.56 2.03(1.42–2.64) -
Type of diabetes Type 1 2 234 8.55 0.18 11.07(7.05–15.09) 1.39(0.32–6.12)
Type2 88 3,546 24.82 35.38 2.49(1.98–3.00) 1
Diabetic foot ulcer (DFU)
All 97 2,280 42.54 22.07 4.39(3.55–5.23) -
gender Men 74 1,418 52.19 18.09 4.09(3.06–5.12) 1.68(1.05–2.71)
Women 23 862 26.68 5.54 4.15(2.82–5.48) 1
Duration of diabetes ≤15 years 7 334 20.96 3.44 2.04(0.52–3.56) 1
>15 years 90 1,946 46.25 18.64 4.83(3.88–5.78) 3.84(1.72–8.56)*
Age < 65 years 40 1,143 35.00 2.33 17.13(14.95–19.31) -
≥ 65 years 57 1,137 50.13 19.74 2.89(1.92–3.86) -
Type of diabetes Type 1 7 148 47.30 0.18 37.91(30.09–45.73) 2.72(1.12–6.57)
Type2 90 2,132 42.21 21.89 4.11(3.27–4.95) 1
Lowe Extrimities Amputation (LEA)
All 98 1,129 86.80 13.59 7.21(5.7–8.72) -
gender Men 76 736 103.26 12.05 6.31(4.55–8.07) 1.43(0.88–2.32)
Women 22 393 55.98 2.65 8.29(5.56–11.02) 1
Duration of diabetes ≤15 years 13 130 100.00 1.38 9.43(4.41–14.45) 1
>15 years 85 999 85.09 12.22 6.96(5.38–8.54) 1.26(0.68–2.33)*
Age < 65 years 40 487 82.14 1.09 36.59(32.31–40.87) -
≥ 65 years 58 642 90.34 12.01 4.83(3.17–6.49) -
Type of diabetes Type 1 3 41 73.17 0.29 10.36(1.03–19.69) 1.04(0.32–3.33)
Type2 95 1,088 87.32 13.3 7.14(5.61–8.67) 1

Adjusted for age at diagnosis and diabetes duration,

* Adjusted for age at diagnosis