Table 5. The pharmacokinetic parameters of M10.
PK parameters | Values |
---|---|
Dose (mg/ kg of mouse body weight) | 1.0 |
AUC 0-48h (ng.h/ml) | 72463 ± 2390 |
Half-life (h) | 6.8 ± 0.7 |
Tmax (h) | 6 |
Cmax (ng/ml) | 4861.5 ± 11.5 |
The half-life, plasma concentrations for AUC and Cmax are presented with the mean ± SD. PK parameters was calculated using GraphPad Prism 7.