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. 2017 Nov 27;12(11):e0188588. doi: 10.1371/journal.pone.0188588

Table 5. The pharmacokinetic parameters of M10.

PK parameters Values
Dose (mg/ kg of mouse body weight) 1.0
AUC 0-48h (ng.h/ml) 72463 ± 2390
Half-life (h) 6.8 ± 0.7
Tmax (h) 6
Cmax (ng/ml) 4861.5 ± 11.5

The half-life, plasma concentrations for AUC and Cmax are presented with the mean ± SD. PK parameters was calculated using GraphPad Prism 7.