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. 2017 Nov 27;12(11):e0188333. doi: 10.1371/journal.pone.0188333

Fig 3. siRNA identifies cell type specificity of genes that modulate replication of Dengue virus (DENV) and Yellow fever virus (YFV).

Fig 3

Vero / HEp2-c cells were reverse transfected with non-targeting control (NTC) / gene specific on-target plus (OTP) siRNAs (50nM) for 48h followed by infection with DENV (A and B) or YFV (C and D). Effect of gene knockdown on viral replication is shown as fold-change relative to NTC from pooled samples. Error bars represent ±SEM from two independent experiments. * p<0.05 **p<0.01 ***p<0.001 ****p<0.0001.