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. 2017 Nov 27;12(11):e0188056. doi: 10.1371/journal.pone.0188056

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© 2017 Tai et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Signal tracks of DNase-hypersensitivity (green), RUNX2 enrichment (blue), and CTCF enrichment (red) at pre-osteoblast, matrix depositing osteoblast, and mineralizing osteoblast stages; encompassing the bone-related genes (A) bone morphogenic protein 2 (Bmp2), (B) bone sialoprotein (Ibsp), (C) Osterix (Sp7), and (D) Distal-less homeobox-2 (Dlx2). The TSSs are designated by forward-facing arrows. 30-way Multiz Alignment and conservation tracks and diagrams of the gene transcripts accompany each track display above. The scales for the normalized signal values are displayed to the right of each track.