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. 2017 Nov 27;12(11):e0188633. doi: 10.1371/journal.pone.0188633

Table 1. Clinical characteristics of the breast cancer patients, tumors treated and surgical procedures.

Variable Frequency (%)
n = 200
Smoking 25.0
Alcohol habit (> 20g/day) 4.5
Arterial hypertension 28.0
Diabetes 8.5
Dyslipidemia 27.5
Chronic obstructive pulmonary disease 4.5
Ischemic heart disease 3.5
Hypothyroidism 9.0
Menopause state
Premenopausal 24.5
Perimenopausal 12.0
Postmenopausal 63.5
Intake of oral contraceptives 30.5
Tumor size (TNM system)
T1 63.0
T2 28.5
T3 6.5
T4 2.0
Nodes (TNM system)
N0 68.0
N1 24.5
N2 6.0
N3 1.5
Metastases (TNM system)
M0 97.0
M1 3.0
Pathological anatomy of the tumor
Ductal carcinoma in situ 7.5
Invasive ductal carcinoma 79.0
Lobular carcinoma in situ 0.5
Invasive lobular carcinoma 1.5
Papillary carcinoma 6.5
Others 5.0
Estrogen receptors
Negative 17.0
Positive 83.0
Progesterone receptors
Negative 32.0
Positive 68.0
Ki67 antigen in tumor biopsy
Less than 15% 42.5
15–50% 44.5
More than 50% 13.0
Her2 receptor in tumor biopsy
Negative 81.0
Positive 19.0
Tumor molecular classification
Luminal A 34.0
Luminal B 36.5
Her2 positive 19.0
Triple negative 10.5
Surgical procedure
Lumpectomy 79.0
Mastectomy 21.0
Adjuvant chemotherapy 60.0
Adjuvant hormone therapy 83.5