Table 2. Effect of early growth (tlag, µ and σb) and control (t̄c, Vc and ntip) parameters on the capacity of the model to predict survival.
Log-likelihood is computed either on bacterial load data (i.e. on the data set we used to fit the model) or on survival data. In this latter case, we used the probability of control predicted by the model as an offset in a binomial general linear model (glm) fitted to survival data. This glm includes an intercept which quantifies the difference between predicted control probability and observed survival. p-values indicate whether keeping a parameter constant for all bacteria significantly alters survival prediction.
| Complete data set | Intermediate survival | ||||||
|---|---|---|---|---|---|---|---|
| Bacterial load | Survival | Bacterial load | Survival | ||||
| df | logLik | logLik | p-value | logLik | logLik | p-value | |
| Full | −1243.119 | −17.85860 | −800.0603 | −11.48770 | |||
| Control | 24 | −1629.965 | −21.68408 | 0.999 | −839.5523 | −17.18319 | 0.496 |
| t̄c | 8 | −1660.396 | −19.18941 | 0.954 | −839.5791 | −16.82534 | 0.030 |
| Vc | 8 | −1643.985 | −17.37663 | 1 | −826.4296 | −14.67760 | 0.173 |
| ntip | 8 | −1634.382 | −25.23397 | 0.064 | −832.8896 | −12.85596 | 0.603 |
| Growth | 24 | −1798.630 | −81.13355 | 6.512e-16 | −854.1100 | −11.37739 | 1 |
| tlag | 8 | −1692.743 | −16.49076 | 1 | −835.3833 | −11.30397 | 1 |
| µ | 8 | −1705.175 | −61.56015 | 1.564e-15 | −836.3794 | −11.75406 | 0.970 |
| σb | 8 | −1704.156 | −21.95270 | 0.415 | −848.2682 | −12.28487 | 0.810 |